Ultimate Comics Enemy (2010) #1
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Characters
Peter’s relatively normal life changed abruptly during a school trip to Osborn Industries, Inc, where the company had been working on a super soldier serum, the Oz Compound; a spider exposed to it escaped and bit Peter before it was destroyed.
When the time came for Reed Richards to demonstrate his teleportation device, his old friend Ben Grimm was invited to observe, but the device malfunctioned and Ben woke up in Mexico City, transformed into a rocky, brutish Thing.