Uncanny X-Men (1981) #231
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Characters
Adam Warlock is an artificially created human who was born in a cocoon at a scientific complex called The Beehive.
Rahne Sinclair was an orphan in Scotland, raised by Reverend Craig, who, when her powers manifested, attempted to perform an exorcism to cast out what he perceived was the devil, after which Rahne was rescued by Doctor Moira MacTaggert who legally adopted her, and was introduced to Charles Xavier and enrolled as part of his New Mutants training team.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.
Feared and hated by humans because they're different, the X-Men are heroic mutants, individuals born with special powers who've sworn to use their gifts to protect mutants as well as humans.